CONJUGATED HYPERBILIRUBINEMIA (CH): A PREDICTOR OF PREINATAL MORTALITY AND POOR NEUROLOGIC OUTCOME

Conjugated hyperbilirubinemia in children.

A variety of anatomic, infectious, autoimmune, and metabolic diseases can lead to conjugated hyperbilirubinemia, both in the newborn period and later in childhood. The pediatric practitioner is most likely to encounter conjugated hyperbilirubinemia in the neonatal period.It is crucial to maintain a high degree of suspicion for cholestasis in the persistently jaundiced newborn. The goal is recog...

Intracerebral hemorrhage volume predicts poor neurologic outcome in children.

BACKGROUND AND PURPOSE Although intracerebral hemorrhage (ICH) volume and location are important predictors of outcome in adults, few data exist in children. METHODS A consecutive cohort of children, including full-term newborns to those younger than 18 years of age with nontraumatic, acute ICH and head CT available for analysis were studied. Clinical information was abstracted via chart revi...

Pediatric Conjugated Hyperbilirubinemia — Diagnosis and Treatment

Race as a predictor of morbidity, mortality, and neurologic events after carotid endarterectomy.

OBJECTIVE Racial disparities in the outcomes of patients undergoing carotid endarterectomy (CEA) have been reported. We sought to examine the contemporary relationship between race and outcomes and to report postdischarge events after CEA. METHODS The American College of Surgeons National Surgical Quality Improvement Program Participant Use Data Files were reviewed to identify all CEAs perfor...

Arteriohepatic dysplasia (Alagille's syndrome): a common cause of conjugated hyperbilirubinemia.

Syndromatic paucity of interlobular bile ducts is a common cause of conjugated hyperbilirubinemia in children. The clinical presentation is not always obvious. Therefore, the liver biopsy may be a useful diagnostic tool in the definition of this entity. The hepatic and biliary morphology of five children with arteriohepatic dysplasia (Allagille' syndrome) is described. Prior to diagnosis, four ...